The Team
Andrea Ganna - Team Lead
Andrea is an Associate Professor at FIMM and HiLIFE and a research associate at Harvard Medical School and Massachusetts General Hospital. Previously he did his post-doc at the Analytical and Translation Genetic Unit at Massachusetts General Hospital/Harvard Medical School/Broad Institute and his PhD at Karolinska Institute. His research interests lie at the intersection between epidemiology, genetics and statistics. His research vision is to integrate genetic data and information from electronic health record/national health registries to enhance early detection of common diseases and enable more effective public health interventions. Andrea is the founder of Real World Genetics Oy.
Tuomo Hartonen – Post-doc
Tuomo is joining the DSGE lab as a post-doctoral researcher working in the INTERVENE-EU project. Tuomo has completed his PhD studies at University of Helsinki, during which he has been developing methods for analysing data from high-throughput genomics experiments, lately focusing especially in applying deep learning to determine the sequence determinants of human enhancers and promoters. He has completed master's degrees both in theoretical physics and in translational medicine. Tuomo has previously worked with analysis and modelling of different types of "Big Data" ranging from predicting contacts in folded proteins to analysing patterns in human mobility from smartphone data.
Pekka Vartiainen - Post-doc
Pekka is a resident doctor in pediatrics and an MD-PhD from University of Helsinki. In his PhD, he studied the health-related quality of life (HRQoL) measurement in capturing treatment effectiveness and the burden of disease in patients with chronic pain. Pekka is also involved in projects of HRQoL measurement and interested in improving the MD education in Finnish universities. As a resident doctor, he has worked in two pediatric hospitals and in primary care. At the DSGE lab, he is working with the FinRegistry data and aiming to model the hospitalization in small children infected with respiratory syncytial virus (RSV). The project ultimately aims for better and cost-effective targeting of novel RSV immunization methods.
Zhiyu Yang - Post-doc
Zhiyu is joining the lab as a post-doctoral researcher after finishing her PhD at Purdue University, USA, focusing on genetics of psychiatric diseases. She is interested in applying different computational and statistical methods to biological data to understand the etiology of human diseases.
She will be working on the INTERVENE-EU project. She hopes her work can help with narrowing the gap between lab discoveries and clinical applications.
Tomoko Nakanishi - Post-doc
Tomoko finished the internal medicine and respirology residency program in Japan. After that, she studied human genetics, in particular genetic epidemiology, during her PhD in Kyoto-McGill joint PhD program. During her PhD, she actively worked on large-scale collaborative research on COVID-19 in COVID-19 Host Genetic Initiative. Tomoko will join the DSGE lab to comprehensively understand both epidemiological and genetic risk factors associate with the onset, progression and/or cost of the diseases.
Sebastian May-Wilson - Post-doc
Sebastian is a post-doctoral researcher in the DSGE lab working on conducting a GWAS of healthcare costs with the multinational GenCOST consortium. This project aims to discover the genetic variation involved in the increasing costs of global healthcare and expand upon existing work in UK Biobank and FinRegistry. Prior to working at the FIMM institute, Sebastian conducted a Masters in Research in the field of molecular genetics at the University of Glasgow, and a PhD in Precision Medicine at the University of Edinburgh. His PhD was primarily focused on developing a novel computational method of analysing biological pathways and their relationship with complex genetic traits (PathWAS). His research interests are largely focused around population genetics and their involvement in global health, including elements of multi-omics, epigenetics and their incorporation with bioinformatics.
Kristina Zguro - Post-doc
Kristina is joining the DSGE lab as a post-doctoral researcher after completing her Ph.D. studies in Genetics, Oncology and Clinical Medicine at the University of Siena. Throughout her doctoral journey, she closely collaborated with the Medical Genetics Unit, focusing extensively on whole-exome sequencing data analysis to identify novel genetic determinants of COVID-19 severity and investigate the clinical variability observed among patients with rare diseases.
Excited to explore new frontiers, Kristina will be now working on cutting-edge research at the intersection of human genetics and economics.
Rodos Rodosthenous - Research coordinator
Rodos is a Molecular Biologist with extensive expertise in Molecular Epidemiology and Biomarker Development. He has a doctoral degree from Harvard University (T.H. Chan School of Public Health) followed by a post-doctoral training as an American Heart Association Fellow at Massachusetts General Hospital and Harvard Medical School. Before joining the DSGE Lab, Rodos worked as a Scientific Consultant in a health-tech/biotech company.
As a member of the DSGE Lab, Rodos will be involved in development projects related to the Finnish national studies FinnGen and FinnRegistry.
Anne Carson – Project coordinator
Anne is a Project Coordinator for the DSGE lab and the INTERVENE-EU Project. Before joining FIMM, Anne worked at the Department of Human Genetics and Pediatrics at University of California, Los Angeles, in various capacities. She has years of experience in research administration and business service management on the departmental level.
Mattia Cordioli - PhD candidate
Mattia completed his Masters degree in Bioengineering at University of Pavia (Italy), focusing on computer and data science.
At the DSGE Lab, Mattia is currently working on integrating nationwide health and socio-economic registries and genetics to better identify predictors of drug adherence. He has previously worked on leveraging genetic data to identify participation bias mechanisms in biobank studies, and on the role of host genetics in COVID-19 disease, as part of the COVID19-HGI consortium.
Feiyi Wang - PhD candidate
Feiyi completed her master degree in Data Science at Worcester Polytechnic Institute in MA, USA. Upon graduation, she worked as an oncology data scientist in pharmaceutical industry. She was also a research fellow at Dana-Farber Cancer Institute, working on patient pathway extraction and clinical analytics platform development using machine learning and NLP techniques. During her Ph.D. study, she is interested in building novel multimodal deep learning models for disease subtype classification and personalized treatment identification with a utilization of multi-omics data, clinical data and medical imaging data.
Lisa Eick - PhD candidate
At the beginning of her bachelor's degree, Lisa focused exclusively on biological questions and how they can be researched in the wetlab. Lisa's complementary studies in computer science, in addition to her master's degree in biomedical sciences at the University of Marburg, sparked her interest in the area between biology and computer science. After her bioinformatics master's thesis, Lisa wanted to continue working in this field.
Therefore, she is interested in applying machine learning algorithms to biological Big Data as part of her PhD.
Essi Viippola - PhD candidate
Essi has graduated from the University of Oulu with a master's degree in statistics. Before joining the DSGELab, she worked as a data scientist and project manager at an ICT company. She has a broad interest in data-related topics, and she's particularly interested in interpretable machine learning. At the DSGELab she will be working on applying statistical methods and machine/deep learning to electronic health records data.
Jakob German – PhD candidate
As the youngest ever graduated pharmacist in German history, Jakob completed his education from the Freie Universität, Berlin.
During and after his studies, he collected valuable experience in the pharmaceutical industry and business.
Having a passion for people's health, he set himself the goal to accelerate developments in health care.
With his constant curiosity and thirst for intellectually demanding challenges, he developed a strong interest in data-related topics and applying computational methods to medical data.
As a PhD candidate and EWSC Fellow of the Broad Institute of MIT and Harvard, Jakob is currently working on the emulation of randomized controlled trials (RCTs) with real-world data (RWD) and investigating multiomics enrichment strategies to improve study designs and advance the implementation of genetics in clinical decision making.
Kira Detrois - Bioinformatician
Kira is currently doing her Master's in Life Science Informatics at the University of Helsinki with a focus on Biostatistics. She holds a bachelor's degree in Applied Computer Science from the University of Göttingen. Already at the start of her Bachelor's, she was interested in applying her skills to biomedical research. This interest was strengthened by her thesis at the Max Planck Institute for Biophysical Chemistry in Göttingen where she worked on connecting trans-eQTLs to complex diseases. She is particularly interested in improving health care and life quality through early and effective detection and intervention of diseases. At the DSGE Lab, she will be working on the INTERVENE project.
Matteo Ferro - Biostatistician
Matteo is a Biostatistics graduate from the University of Milano-Bicocca. He wrote his thesis entitled "Clustered Statin Adherence Trajectories:A Study on Disease Onset" working with the help of DSGE lab and using Finregistry's medication purchase datasets. His interests range from longitudinal and survival analysis to modern techniques like deep learning, all to be applied to real-world health data.
Ville Pinto de Andrade Anapaz - Master student
Ville is a bachelor's degree student studying mathematics and statistics at the University of Helsinki. He will be interning this summer and will be working on the Family aggregation of diseases in the isolated Finnish population using both FinnGen and FinRegistry data project. His interests lie in applying statistical methods and deep/machine learning approaches to complex real world problems.
Andrea Corbetta - visiting PhD student
Andrea graduated in Biostatistics from the University of Milano-Bicocca. For his master’s thesis, he has been a visiting researcher at FIMM in DSGE Lab. He worked on the genetic-environmental determinants of drug adherence and the COVID19-HGI project. He is now a PhD student at the Polytechnic University of Milan and Human Technopole in the Health Data Science Center. He is working on expanding ML and statistical methods in both Finnish and Italian health registries.
Yipeng Cheng - visiting PhD student
Yipeng is a PhD student in the DSGE lab working on risk prediction models for type 2 diabetes, incorporating a wide range of information from electronic health records, genetics and DNA methylation. His current focus is on assessing robustness of EHR-based risk scores across different healthcare systems, utilising data from both the FinnGen and Generation Scotland studies.
Prior to his PhD, he worked on applications of machine learning at BT Research before pursuing his interest in bioinformatics in his master’s studies at Newcastle University.
Previous group members
Ettore Brenna - Master student
Anna-Leena Vuorinen - Senior Scientist
Joanne Demmler - Data Manager
Giulia Brunelli - visiting PhD student
Matthias Kirchler - visiting PhD student
Aoxing Liu - Post-doc
Sölvi Rögnvaldsson - Master student
Antti Karvanen – research assistant
Andrius Vabalas – Post-doc
Sakari Jukarainen – Post-doc
Alexandra Prinz - Rotation MD-PhD student
Kristina Zguro - visiting PhD student
Sara Kuitunen – Software developer
Linzi Yu - visiting student
Jiwoo Lee – Bioinformatician
Yllza Zogjani – research assistant
Vincent Llorens - Software Developer
Mari Niemi - Post-doc
Sara Pigazzini - Research assistant
Mads Nordentoft - Epidemiologist
Timo Syvälahti, MD-PhD rotation student
Atte Fohr, Summer intern
Takao Shimizu, Visiting student
Joona Savela, Visiting summer student